Albatroz Therapeutics

In the News

11/07/2023

Albatroz Co-Founder and CEO, Dr. Fredric Bard is spotlighted by A*STAR – Agency for Science, Technology and Research for his insights as a scientist-entrepreneur

10/18/2023

Albatroz Named One of Six Companies Leading Singapore’s Biotech Scene

10/10/2023

Albatroz Featured in the Novo Nordisk Singapore Partnering Day 2023
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Publications

ER-resident oxidoreductases are glycosylated and trafficked to the cell surface to promote matrix degradation by tumour cells.

Nat. Cell Biol. 22(11) 1371–1381 (2020). DOI: 10.1038/s41556-020-00590-w

Src activates retrograde membrane traffic through phosphorylation of GBF1.

eLife. 10:268678 (2021). ​DOI: 10.7554/eLife.68678

The GalNAc-T Activation (GALA) Pathway: Drivers and markers.

PLoS One. 19;14(3):e0214118 (2019). DOI: 10.1371/journal.pone.0214118

Organelle Specific O-Glycosylation Drives MMP14 Activation, Tumor Growth, and Metastasis.

Cancer Cell. 13;32(5):639-653.e6 (2017). DOI: 10.1016/j.ccell.2017.10.001

Cracking the glycome encoder: signaling, trafficking, and glycosylation.

Trends Cell Biol. 26, 379–388 (2016). DOI: 10.1016/j.tcb.2015.12.004

Short O-GalNAc glycans: regulation and role in tumor development and clinical perspectives.

Biochim Biophys Acta. 1860(8):1623-39 (2016). DOI: 10.1016/j.bbagen.2016.03.008

ERK8 is a negative regulator of O-GalNAc glycosylation and cell migration.

eLife 3, e01828 (2014). DOI: 10.7554/eLife.01828

Initiation of GalNAc-type O-glycosylation in the endoplasmic reticulum promotes cancer cell invasiveness.

Proc. Natl Acad. Sci. USA 110, E3152–E3161 (2013). DOI: 10.1073/pnas.1305269110

Regulation of O-glycosylation through Golgi-to-ER relocation of initiation enzymes.

J. Cell Biol. 189(5):843-858 (2010). ​DOI: 10.1083/jcb.201003055

GALA drives arthritis and cartilage degradation by synovial fibroblasts.

(manuscript in preparation).